ATTACHMENT, NEUROBIOLOGY, AND MENTALIZING ALONG THE PSYCHOSIS CONTINUUM

Attachment, neurobiology, and mentalizing along the psychosis continuum

Attachment, neurobiology, and mentalizing along the psychosis continuum

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In this review article, we outline the evidence linking attachment adversity to the psychosis, from the premorbid stages of the disorder to its clinical forms.To better understand the neurobiological mechanisms through which insecure attachment may contribute to psychosis, we identify at least five neurobiological pathways linking attachment to risk for developing psychosis.Besides its well documented influence on the hypothalamic-pituary-adrenal (HPA) axis, insecure attachment may also contribute to neurodevelopmental risk through taotao gk110 go kart parts the dopaminergic and oxytonergic systems, as well as bear influence on neuroinflammation and oxidative stress responses.

We further consider the neuroscientific and behavioural studies that underpin mentalization as a suite of processes potentially moderating the risk to transition to psychotic disorders.In particular, mentalization may help the individual compensate mighty malts speckled malted milk eggs for endophenotypical impairments in the integration of sensory and metacognitive information.We propose a model where embodied mentalization would lie at the core of a protective, resilience response mitigating the adverse and potentially pathological influence of the neurodevelopmental cascade of risk for psychosis.

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